Ace View of Cenix:300-f2 | |||
Gene Inhibited | R107.6 (cls-2) | ||
Description of "R107.6" | cls-2 encodes one of three predicted orthologs of mammalian CLASPs and of Drosophila ORBIT/MAST, microtubule-binding proteins required for fibroblast polarization and mitosis; cls-2 is required in mass RNAi assays for embryonic development and normal mitotic spindles; it has been claimed that, in an RNAi screen of potential microtubule tip-binding proteins, only cls-2(RNAi) yielded embryonic lethality and meiotic defects. | ||
KOG Annotation  | CLIP-associating protein |
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Evidence for Inhibition | |||
External "R107.6" Links | ![]() ![]() ![]() |
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Embryonic | Emb Penetrance None reported | ||
Phenotype | Chromosome Segregation (karyomeres) abnormal |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:300-f2 (PCR_reagent) | ||
Remark | early embryonic: Chromosome Segregation (karyomeres) | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of R107.6 | |||
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