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RNAi Experiment: Cenix:300-f2 Ace View of Cenix:300-f2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R107.6 (cls-2)
Description of "R107.6"  cls-2 encodes one of three predicted orthologs of mammalian CLASPs and of Drosophila ORBIT/MAST, microtubule-binding proteins required for fibroblast polarization and mitosis; cls-2 is required in mass RNAi assays for embryonic development and normal mitotic spindles; it has been claimed that, in an RNAi screen of potential microtubule tip-binding proteins, only cls-2(RNAi) yielded embryonic lethality and meiotic defects.
KOG Annotation  CLIP-associating protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9056116..9057048)
Transcript overlap: 870 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 828
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R107.6" Links  Wormbase NCBI Phenobank 1
Cenix:300-f2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Chromosome Segregation (karyomeres) abnormal
External Movies 
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Cenix:300-f2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:300-f2 (PCR_reagent)
Remark  early embryonic: Chromosome Segregation (karyomeres)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of R107.6 Browse using GBrowse
Gene Graph