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RNAi Experiment: Cenix:302-a12 Ace View of Cenix:302-a12
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F10E9.6 (mig-10)
Description of "F10E9.6"  mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head.
KOG Annotation  Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:8303081..8304758)
Transcript overlap: 1051 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 988
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F10E9.6" Links  Wormbase NCBI Phenobank 1 2
Cenix:302-a12 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:302-a12 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:302-a12 (PCR_reagent)
Remark  wild type
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F10E9.6 Browse using GBrowse
Gene Graph