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RNAi Experiment: Cenix:305-c3 Ace View of Cenix:305-c3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20H4.5
Description of "T20H4.5"  The T20H4.5 gene encodes an ortholog of the human gene NADH DEHYDROGENASE-UBIQUINONE FE-S PROTEIN 8 23 KDA SUBUNIT; MITOCHONDRIAL COMPLEX I TYKY SUBUNIT (NDUFS8; OMIM:602141), which when mutated leads to Leigh syndrome (OMIM:256000); the T20H4.5 protein is predicted to be mitochondrial with 52% accuracy.
KOG Annotation  NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7233091..7234966)
Transcript overlap: 695 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 611
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T20H4.5" Links  Wormbase NCBI Phenobank 1
Cenix:305-c3 Phenotypes Help with Phenotypes
Phenotype  Larval Arrest-Early (L1/L2)
External Movies 
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Cenix:305-c3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:305-c3 (PCR_reagent)
Remark  early embryonic: All embryos show a significant drop in the overall pace of events.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T20H4.5 Browse using GBrowse
Gene Graph