Link to T20B12.7.1Link to T20B12.7.2Link to T20B12.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to C32F10.2Link to C32F10.5RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:305-h4 Ace View of Cenix:305-h4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20B12.8 (hmg-4)
Description of "T20B12.8"  hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development.
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7379412..7381572)
Transcript overlap: 1883 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1778
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.939
Wormbase (BLAST) RNAi primary
External "T20B12.8" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  C32F10.5 (hmg-3)
Description of "C32F10.5"  Associated GO Term : DNA binding
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 115
Relative score: 0.065 (Best raw score= for Gene )
Specificity index: 0.061
Wormbase (BLAST) RNAi secondary
External "C32F10.5" Links  Wormbase NCBI Phenobank 1
Cenix:305-h4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
(Please note that RNAiDB is not
hosting these data.)
/static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Help
Cenix:305-h4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:305-h4 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T20B12.8 Browse using GBrowse
Gene Graph
Gene Plot of C32F10.5 Browse using GBrowse
Gene Graph