Ace View of Cenix:305-h4 | ||||||
Gene Inhibited | T20B12.8 (hmg-4) | |||||
Description of "T20B12.8" | hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development. | |||||
KOG Annotation  | Nucleosome-binding factor SPN, POB3 subunit |
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Evidence for Inhibition | ||||||
External "T20B12.8" Links | 1 | |||||
Gene Inhibited | C32F10.5 (hmg-3) | |||||
Description of "C32F10.5" | Associated GO Term : DNA binding | |||||
KOG Annotation  | Nucleosome-binding factor SPN, POB3 subunit |
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Evidence for Inhibition |
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External "C32F10.5" Links | 1 | |||||
Embryonic | Emb Penetrance None reported | |||||
Phenotype | WT_postembryonic_morphology |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | |||||
RNAi Reagent & Type | Cenix:305-h4 (PCR_reagent) | |||||
Remark | early embryonic: No significant defects. | |||||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | |||||
Delivery Method | Injection | |||||
Date | 2005-3-24 | |||||
Gene Plot of T20B12.8 | ||||||
Gene Plot of C32F10.5 | ||||||