| RNAi Experiment: Cenix:306-c12 |
Ace View of Cenix:306-c12
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| Genes Inhibited |
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| Gene Inhibited |
C05D11.3 |
| Description of "C05D11.3" |
C05D11.3 encodes an ortholog of APACD (ATP binding protein associated with cell differentiation) conserved in eukaryotes; C05D11.3 has a thioredoxin-like domain, probably lacking catalytic activity; mouse APACD is both cytoplasmic and nuclear, often localized to centrosomes and midbody; C05D11.3 is expressed in all developmental stages, preferentially in neurons and vulva; C05D11.3 is required for normal mitotic spindle formation, pronuclear migration and nuclear-centrosome rotation. |
| KOG Annotation |
ATP binding protein
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:6432273..6433041)
Transcript overlap: 515 nt |
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| Sliding Window |
Raw score: 473
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "C05D11.3" Links |
   1 |
| Cenix:306-c12 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Pnm
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:306-c12 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:306-c12 (PCR_reagent) |
| Remark |
early embryonic: Pronuclear Migration |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of C05D11.3 |
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