RNAi Experiment: Cenix:308-b1 |
Ace View of Cenix:308-b1
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Genes Inhibited |
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Gene Inhibited |
F59B2.6 (zif-1) |
Description of "F59B2.6" |
zif-1 encodes a SOCS-box protein that promotes establishment of the germ line by targetting germline proteins for cullin-dependent degradation in non-germline (somatic) cells; ZIF-1 binds germline CCCH-(zinc)-finger proteins and the E3 ubiquitin ligase subunit elongin C (ELC-1); while ZIF-1 has no obvious homologs, it may be analogous to the Drosophila SOCS-box protein GUSTAVUS, which is required for VASA localization to the germline and which does have mammalian homologs. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:9002781..9004416)
Transcript overlap: 1367 nt |
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Sliding Window |
Raw score: 1241
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F59B2.6" Links |
1 |
Cenix:308-b1 Phenotypes |
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Phenotype |
WT
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Cenix:308-b1 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:308-b1 (PCR_reagent) |
Remark |
wild type |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of F59B2.6 |
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