Ace View of Cenix:309-h9 | |||
Gene Inhibited | C06G4.2 (clp-1) | ||
Description of "C06G4.2" | clp-1 encodes a calpain homolog that has significant identity to mammalian calpains over its whole length and that contains motifs typical of calpains, including a thiol (cysteine) protease active site and a Ca[2+]-binding domain; CLP-1 is required, in parallel with TRA-3 but in series with ASP-3 and ASP-3, for degenerative (necrotic-like) cell death in neurons induced by mutations such as mec-4(d), deg-3(d), or gsa-1(gf). | ||
Evidence for Inhibition | |||
External "C06G4.2" Links | 1 2 3 4 | ||
Phenotype | WT |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:309-h9 (PCR_reagent) | ||
Remark | wild type | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C06G4.2 | |||