| RNAi Experiment: Cenix:314-c10 |
Ace View of Cenix:314-c10
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| Genes Inhibited |
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| Gene Inhibited |
F10E9.6 (mig-10) |
| Description of "F10E9.6" |
mig-10 encodes a protein containing a pleckstrin homology domain and a proline-rich region, and is similar to the SH2-domain containing adapter proteins Grb7 and Grb10 which are involved in receptor tyrosine kinase-mediated signal transduction; MIG-10 is likely required for signal transduction during cell migration, as it is required non-cell autonomously for excretory canal development and anterior-posterior migrations of the embryonic neurons ALM, CAN, and HSN; mig-10 mutations appear to interact genetically with mutations in all three C. elegans rac genes, ced-10, mig-2, and rac-2, suggesting partial redundancy during neuronal migration and excretory canal outgrowth; MIG-10 is expressed in many embryonic cells and in four cells in the adult head. |
| KOG Annotation |
Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:8281654..8282503)
Transcript overlap: 250 nt |
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| Sliding Window |
Raw score: 229
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "F10E9.6" Links |
   1 |
| Cenix:314-c10 Phenotypes |
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| Phenotype |
WT
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| Cenix:314-c10 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:314-c10 (PCR_reagent) |
| Remark |
wild type |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of F10E9.6 |
Browse using GBrowse
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