Link to Y47D3B.6Link to Y47D3B.7RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to Y49F6C.6RNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: Cenix:325-g3 Ace View of Cenix:325-g3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y47D3B.7 (sbp-1)
Description of "Y47D3B.7"  sbp-1 encodes a basic helix-loop-helix (bHLH) transcription factor homologous to the mammalian Sterol Regulatory Element Binding Proteins (SREBPs, OMIM:184756, overexpression of nuclear form of SREBP-1c is associated with insulin resistance and features of congenital generalized lipodystrophy); in C. elegans, SBP-1 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for embryonic and larval development; sbp-1 expression is detected exclusively in the intestine, the major site of fat storage, from early embryogenesis through adulthood.
KOG Annotation  Predicted DNA-binding protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:11436957..11438643)
Transcript overlap: 1228 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1135
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.901
Wormbase (BLAST) RNAi primary
External "Y47D3B.7" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  Y49F6C.6
Evidence for Inhibition 
Sliding Window Raw score: 125
Relative score: 0.11 (Best raw score= for Gene )
Specificity index: 0.099
External "Y49F6C.6" Links  Wormbase NCBI Phenobank 1
Cenix:325-g3 Phenotypes Help with Phenotypes
Phenotype  Larval Lethal-Early (L1/L2)
External Movies 
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hosting these data.)
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Cenix:325-g3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:325-g3 (PCR_reagent)
Remark  post-embryonic: Larval Lethal-Early (L1/L2)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y47D3B.7 Browse using GBrowse
Gene Graph
Gene Plot of Y49F6C.6 Browse using GBrowse
Gene Graph