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RNAi Experiment: Cenix:329-f9 Ace View of Cenix:329-f9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T07C4.4 (spp-1)
Description of "T07C4.4"  spp-1 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-1 is predicted to function as a lipid-binding protein with cytotoxic, pore-forming activity, and in vitro, does exhibit antibacterial activity; loss of SPP-1 function via RNA-mediated interference (RNAi) does not, however, result in any abnormalities.
Evidence for Inhibition 
ePCR Status: Best_ePCR (III:10354827..10355762)
Transcript overlap: 498 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 456
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.685
Wormbase (BLAST) RNAi primary
External "T07C4.4" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T07C4.1
Description of "T07C4.1"  T07C4.1 is orthologous to the human gene URIDINE MONOPHOSPHATE SYNTHETASE (OROTATE PHOSPHORIBOSYL TRANSFERASE AND OROTIDINE-5'-DECARBOXYLASE) (UMPS; OMIM:258900), which when mutated leads to disease.
KOG Annotation  Uridine 5'- monophosphate synthase/orotate phosphoribosyltransferase
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 78 nt Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 78
Relative score: 0.171 (Best raw score= for Gene )
Specificity index: 0.117
External "T07C4.1" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T07C4.3
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (III:10354827..10355762)
Transcript overlap: 153 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 132
Relative score: 0.289 (Best raw score= for Gene )
Specificity index: 0.198
External "T07C4.3" Links  Wormbase NCBI Phenobank 1
Cenix:329-f9 Phenotypes Help with Phenotypes
Phenotype  WT
Cenix:329-f9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:329-f9 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T07C4.1 Browse using GBrowse
Gene Graph
Gene Plot of T07C4.4 Browse using GBrowse
Gene Graph
Gene Plot of T07C4.3 Browse using GBrowse
Gene Graph