RNAi Experiment: Cenix:329-f9 |
Ace View of Cenix:329-f9
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Genes Inhibited |
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Gene Inhibited |
T07C4.4 (spp-1) |
Description of "T07C4.4" |
spp-1 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-1 is predicted to function as a lipid-binding protein with cytotoxic, pore-forming activity, and in vitro, does exhibit antibacterial activity; loss of SPP-1 function via RNA-mediated interference (RNAi) does not, however, result in any abnormalities. |
Evidence for Inhibition |
ePCR |
Status: Best_ePCR (III:10354827..10355762)
Transcript overlap: 498 nt |
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Sliding Window |
Raw score: 456
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.685 |
Wormbase (BLAST) |
RNAi primary |
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External "T07C4.4" Links |
1 |
Gene Inhibited |
T07C4.1 |
Description of "T07C4.1" |
T07C4.1 is orthologous to the human gene URIDINE MONOPHOSPHATE SYNTHETASE (OROTATE PHOSPHORIBOSYL TRANSFERASE AND OROTIDINE-5'-DECARBOXYLASE) (UMPS; OMIM:258900), which when mutated leads to disease. |
KOG Annotation  |
Uridine 5'- monophosphate synthase/orotate phosphoribosyltransferase
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Evidence for Inhibition |
ePCR |
Transcript overlap: 78 nt |
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Sliding Window |
Raw score: 78
Relative score: 0.171 (Best raw score= for Gene )
Specificity index: 0.117 |
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External "T07C4.1" Links |
1 |
Gene Inhibited |
T07C4.3 |
Evidence for Inhibition |
ePCR |
Status: Bottom50_percentile_ePCR (III:10354827..10355762)
Transcript overlap: 153 nt |
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Sliding Window |
Raw score: 132
Relative score: 0.289 (Best raw score= for Gene )
Specificity index: 0.198 |
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External "T07C4.3" Links |
1 |
Cenix:329-f9 Phenotypes |
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Phenotype |
WT
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Cenix:329-f9 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
Cenix:329-f9 (PCR_reagent) |
Remark |
early embryonic: No significant defects. |
Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
Delivery Method |
Injection |
Date |
2005-3-24 |
Gene Plot of T07C4.1 |
Browse using GBrowse
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Gene Plot of T07C4.4 |
Browse using GBrowse
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Gene Plot of T07C4.3 |
Browse using GBrowse
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