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RNAi Experiment: Cenix:331-g6 Ace View of Cenix:331-g6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y49E10.1 (rpt-6)
Description of "Y49E10.1"  rpt-6 encodes a triple A ATPase that is a subunit of the 26S proteasome 19S regulatory particle (RP) base subcomplex; RPT-6 is required for embryonic and larval development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
KOG Annotation  26S proteasome regulatory complex, ATPase RPT6
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:12370337..12371999)
Transcript overlap: 917 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 838
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y49E10.1" Links  Wormbase NCBI Phenobank 1
Cenix:331-g6 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Sister Chromatid Separation abnormal (Cross-eyed)
External Movies 
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Cenix:331-g6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:331-g6 (PCR_reagent)
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y49E10.1 Browse using GBrowse
Gene Graph