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RNAi Experiment: Cenix:331-h6 Ace View of Cenix:331-h6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y49E10.2
Description of "Y49E10.2"  This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial.
KOG Annotation  Glutaredoxin-related protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:12372438..12373911)
Transcript overlap: 506 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 464
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.682
Wormbase (BLAST) RNAi primary
External "Y49E10.2" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  Y49E10.1 (rpt-6)
Description of "Y49E10.1"  rpt-6 encodes a triple A ATPase that is a subunit of the 26S proteasome 19S regulatory particle (RP) base subcomplex; RPT-6 is required for embryonic and larval development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
KOG Annotation  26S proteasome regulatory complex, ATPase RPT6
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 55 nt Explain types of evidence for RNAi inhibition
External "Y49E10.1" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  Y37H9A.5
Evidence for Inhibition 
Sliding Window Raw score: 123
Relative score: 0.265 (Best raw score= for Gene )
Specificity index: 0.181
Wormbase (BLAST) RNAi primary
External "Y37H9A.5" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T06A10.2
Description of "T06A10.2"  Associated GO Term : structural constituent of ribosome
KOG Annotation  60S ribosomal protein L29
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 93
Relative score: 0.2 (Best raw score= for Gene )
Specificity index: 0.137
Wormbase (BLAST) RNAi primary
External "T06A10.2" Links  Wormbase NCBI Phenobank 1
Cenix:331-h6 Phenotypes Help with Phenotypes
Phenotype  Larval Arrest-Early (L1/L2)
External Movies 
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hosting these data.)
/static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
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Cenix:331-h6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:331-h6 (PCR_reagent)
Remark  post-embryonic: Larval Arrest-Early (L1/L2)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y49E10.1 Browse using GBrowse
Gene Graph
Gene Plot of Y37H9A.5 Browse using GBrowse
Gene Graph
Gene Plot of T06A10.2 Browse using GBrowse
Gene Graph
Gene Plot of Y49E10.2 Browse using GBrowse
Gene Graph