| Ace View of Cenix:333-b2 | |||||||||
| Gene Inhibited | Y111B2A.18 (rsp-3) | ||||||||
| Description of "Y111B2A.18" | rsp-3 encodes a putative ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro and the mRNA of rsp-3 is predominantly expressed in the germline. | ||||||||
| KOG Annotation | Alternative splicing factor ASF/SF2 (RRM superfamily) |
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| Evidence for Inhibition |
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| External "Y111B2A.18" Links |    1 2 |
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| Gene Inhibited | Y111B2A.17 | ||||||||
| Description of "Y111B2A.17" | Associated GO Term : structural constituent of ribosome | ||||||||
| KOG Annotation | RNA polymerase II elongator complex, subunit ELP2, WD repeat superfamily |
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| Evidence for Inhibition |
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| External "Y111B2A.17" Links | 1 2 |
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| Phenotype | Larval Lethal-Early (L1/L2) |
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| External Movies (Please note that RNAiDB is not hosting these data.) |
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| Laboratory | TH | ||||||||
| RNAi Reagent & Type | Cenix:333-b2 (PCR_reagent) | ||||||||
| Remark | post-embryonic: Larval Lethal-Early (L1/L2) | ||||||||
| Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2005-3-24 | ||||||||
| Gene Plot of Y111B2A.17 | |||||||||
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| Gene Plot of Y111B2A.18 | |||||||||
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