Link to Y54E5B.2Link to Y54E5B.3aLink to Y54E5B.3bRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
RNAi Experiment: Cenix:34-c8 Ace View of Cenix:34-c8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y54E5B.3 (let-49)
Description of "Y54E5B.3"  let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1.
KOG Annotation  Transcriptional coactivator
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:14820407..14821733)
Transcript overlap: 809 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 662
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y54E5B.3" Links  Wormbase NCBI Phenobank 1 2
Cenix:34-c8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
(Please note that RNAiDB is not
hosting these data.)
/static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Cenix:34-c8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:34-c8 (PCR_reagent)
Remark  early embryonic: Clear cut result.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y54E5B.3 Browse using GBrowse
Gene Graph