Ace View of Cenix:34-e11 | |||
Gene Inhibited | C25A11.4 (ajm-1) | ||
Description of "C25A11.4" | ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. | ||
Evidence for Inhibition | |||
External "C25A11.4" Links | 1 2 | ||
Phenotype | WT |
||
External Movies (Please note that RNAiDB is not hosting these data.) |
|||
Laboratory | TH | ||
RNAi Reagent & Type | Cenix:34-e11 (PCR_reagent) | ||
Remark | early embryonic: Not the best quality for some of the recordings. However, all events are sufficiently captured to evaluate this test as wildtype. | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C25A11.4 | |||