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RNAi Experiment: Cenix:34-e11 Ace View of Cenix:34-e11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C25A11.4 (ajm-1)
Description of "C25A11.4"  ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:9111724..9113413)
Transcript overlap: 1110 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 963
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C25A11.4" Links  Wormbase NCBI Phenobank 1 2
Cenix:34-e11 Phenotypes Help with Phenotypes
Phenotype  WT
External Movies 
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Cenix:34-e11 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:34-e11 (PCR_reagent)
Remark  early embryonic: Not the best quality for some of the recordings. However, all events are sufficiently captured to evaluate this test as wildtype.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C25A11.4 Browse using GBrowse
Gene Graph