Link to T07C4.7.1Link to T07C4.7.2Link to T07C4.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T07C4.8Link to T07C4.7.1geneMap Link to T07C4.7.1Link to T07C4.7.2Link to T07C4.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T07C4.8Link to T07C4.7.1geneMap Link to Y67H2A.8.2Link to Y67H2A.8.1RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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RNAi Experiment: Cenix:341-c7 Ace View of Cenix:341-c7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T07C4.8 (ced-9)
Description of "T07C4.8"  ced-9 is required for control of programmed cell death during development; it encodes the only C. elegans homolog of BCL-2.
KOG Annotation  Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (III:10335476..10336937)
Transcript overlap: 444 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 360
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.607
Wormbase (BLAST) RNAi primary
External "T07C4.8" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  T07C4.7 (mev-1)
Description of "T07C4.7"  mev-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT C, INTEGRAL MEMBRANE PROTEIN, 15KD (SDHC; OMIM:602413), which when mutated leads to familial nonchromaffin paragangliomas type 3.
KOG Annotation  Succinate dehydrogenase, cytochrome b subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (III:10335476..10336937)
Transcript overlap: 120 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 99
Relative score: 0.275 (Best raw score= for Gene )
Specificity index: 0.167
External "T07C4.7" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  Y67H2A.9
Evidence for Inhibition 
Sliding Window Raw score: 134
Relative score: 0.372 (Best raw score= for Gene )
Specificity index: 0.226
External "Y67H2A.9" Links  Wormbase NCBI Phenobank 1
Cenix:341-c7 Phenotypes Help with Phenotypes
External Movies 
(Please note that RNAiDB is not
hosting these data.)
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Cenix:341-c7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:341-c7 (PCR_reagent)
Remark  post-embryonic: Ambiguous result
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T07C4.8 Browse using GBrowse
Gene Graph
Gene Plot of T07C4.7 Browse using GBrowse
Gene Graph
Gene Plot of Y67H2A.9 Browse using GBrowse
Gene Graph