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RNAi Experiment: Cenix:341-c8 Ace View of Cenix:341-c8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y47D3B.7 (sbp-1)
Description of "Y47D3B.7"  sbp-1 encodes a basic helix-loop-helix (bHLH) transcription factor homologous to the mammalian Sterol Regulatory Element Binding Proteins (SREBPs, OMIM:184756, overexpression of nuclear form of SREBP-1c is associated with insulin resistance and features of congenital generalized lipodystrophy); in C. elegans, SBP-1 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for embryonic and larval development; sbp-1 expression is detected exclusively in the intestine, the major site of fat storage, from early embryogenesis through adulthood.
KOG Annotation  Predicted DNA-binding protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:11436958..11437678)
Transcript overlap: 616 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 566
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y47D3B.7" Links  Wormbase NCBI Phenobank 1
Cenix:341-c8 Phenotypes Help with Phenotypes
External Movies 
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Cenix:341-c8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:341-c8 (PCR_reagent)
Remark  post-embryonic: Adult Phenotype-Other
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y47D3B.7 Browse using GBrowse
Gene Graph