| RNAi Experiment: Cenix:341-g10 |
Ace View of Cenix:341-g10
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| Genes Inhibited |
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| Gene Inhibited |
ZK637.8 (unc-32) |
| Description of "ZK637.8" |
unc-32 encodes six isoforms of a highly conserved vacuolar H+-ATPase a subunit (V-ATPase) homologous to the vertebrate a1 proteins that have been implicated in a number of human diseases including osteopetrosis (OMIM:259700); UNC-32 is predicted to function as part of an ATP-dependent proton pump that regulates acidification of intracellular compartments and is essential for locomotion and embryonic and larval development; UNC-32 is expressed throughout the life cycle, with early and broad expression detectable in the embryo, and larval and adult expression detectable in the gut, gonad, and neurons. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:8907581..8909051)
Transcript overlap: 1380 nt |
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| Sliding Window |
Raw score: 1339
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "ZK637.8" Links |
   1 2 3 4 5 6 |
| Cenix:341-g10 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Pace of P-Lineage abnormal
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External Movies
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hosting these data.) |
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| Cenix:341-g10 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:341-g10 (PCR_reagent) |
| Remark |
early embryonic: Pace of P-Lineage |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of ZK637.8 |
Browse using GBrowse
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