Ace View of Cenix:341-g10 | |||
Gene Inhibited | ZK637.8 (unc-32) | ||
Description of "ZK637.8" | unc-32 encodes six isoforms of a highly conserved vacuolar H+-ATPase a subunit (V-ATPase) homologous to the vertebrate a1 proteins that have been implicated in a number of human diseases including osteopetrosis (OMIM:259700); UNC-32 is predicted to function as part of an ATP-dependent proton pump that regulates acidification of intracellular compartments and is essential for locomotion and embryonic and larval development; UNC-32 is expressed throughout the life cycle, with early and broad expression detectable in the embryo, and larval and adult expression detectable in the gut, gonad, and neurons. | ||
Evidence for Inhibition | |||
External "ZK637.8" Links | 1 2 3 4 5 6 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | Pace of P-Lineage abnormal |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:341-g10 (PCR_reagent) | ||
Remark | early embryonic: Pace of P-Lineage | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of ZK637.8 | |||