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RNAi Experiment: Cenix:35-h7 Ace View of Cenix:35-h7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T05E11.2
Description of "T05E11.2"  T05E11.2 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; T05E11.2 is worm-specific, with a with highly divergent sequence lacking obvious homologs; T05E11.2 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:11114806..11116465)
Transcript overlap: 539 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 434
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T05E11.2" Links  Wormbase NCBI Phenobank 1
Cenix:35-h7 Phenotypes Help with Phenotypes
Phenotype  WT
External Movies 
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Cenix:35-h7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:35-h7 (PCR_reagent)
Remark  There were good numbers of progeny in all three tests. No morphological abnormalities were seen.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of T05E11.2 Browse using GBrowse
Gene Graph