Ace View of Cenix:36-a2 | |||
Gene Inhibited | C37C3.6 (ppn-1) | ||
Description of "C37C3.6" | C37C3.6 encodes three isoforms of a large, novel multidomain glycoprotein orthologous to thrombospondin from Haemonchus contortus, papilin from D. melanogaster, and lacunin from Manduca sexta; the N-terminal region of C37C3.6 proteins have a domain set also found in the C-terminal region of ADAMTS matrix-associated metalloproteinases; C37C3.6 is generally required for normal cell arrangements, being required in embryos for viability and normal hypodermal enclosure, and in L1 larvae for normal excretory canal function. | ||
Evidence for Inhibition | |||
External "C37C3.6" Links | 1 2 3 | ||
Phenotype | Larval Arrest-Late (L3/L4) |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:36-a2 (PCR_reagent) | ||
Remark | early embryonic: No significant defects. | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C37C3.6 | |||