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RNAi Experiment: Cenix:36-a2 Ace View of Cenix:36-a2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C37C3.6 (ppn-1)
Description of "C37C3.6"  C37C3.6 encodes three isoforms of a large, novel multidomain glycoprotein orthologous to thrombospondin from Haemonchus contortus, papilin from D. melanogaster, and lacunin from Manduca sexta; the N-terminal region of C37C3.6 proteins have a domain set also found in the C-terminal region of ADAMTS matrix-associated metalloproteinases; C37C3.6 is generally required for normal cell arrangements, being required in embryos for viability and normal hypodermal enclosure, and in L1 larvae for normal excretory canal function.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:7833205..7833746)
Transcript overlap: 542 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 521
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C37C3.6" Links  Wormbase NCBI Phenobank 1 2 3
Cenix:36-a2 Phenotypes Help with Phenotypes
Phenotype  Larval Arrest-Late (L3/L4)
External Movies 
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Cenix:36-a2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:36-a2 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C37C3.6 Browse using GBrowse
Gene Graph