| RNAi Experiment: Cenix:36-c2 |
Ace View of Cenix:36-c2
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| Genes Inhibited |
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| Gene Inhibited |
C47E12.5 (uba-1) |
| Description of "C47E12.5" |
uba-1 encodes a ubiquitin-activating enzyme orthologous to Saccharomyces cerevisiae UBA1 and human UBE1; UBA-1 is essential for embryogenesis and is required for germline development; by homology, UBA-1 is predicted to function in an ATP-dependent reaction that activates ubiquitin prior to its conjugation to proteins that will subsequently be degraded by the 26S proteasome; a uba-1 transcriptional reporter fusion is expressed in the larval intestine. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (IV:9990810..9991342)
Transcript overlap: 533 nt |
|
| Sliding Window |
Raw score: 512
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "C47E12.5" Links |
   1 |
| Cenix:36-c2 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
Passage Through Meiosis defective
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:36-c2 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:36-c2 (PCR_reagent) |
| Remark |
early embryonic: Passage Through Meiosis |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of C47E12.5 |
Browse using GBrowse
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