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RNAi Experiment: Cenix:36-c2 Ace View of Cenix:36-c2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C47E12.5 (uba-1)
Description of "C47E12.5"  uba-1 encodes a ubiquitin-activating enzyme orthologous to Saccharomyces cerevisiae UBA1 and human UBE1; UBA-1 is essential for embryogenesis and is required for germline development; by homology, UBA-1 is predicted to function in an ATP-dependent reaction that activates ubiquitin prior to its conjugation to proteins that will subsequently be degraded by the 26S proteasome; a uba-1 transcriptional reporter fusion is expressed in the larval intestine.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:9990810..9991342)
Transcript overlap: 533 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 512
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C47E12.5" Links  Wormbase NCBI Phenobank 1
Cenix:36-c2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Passage Through Meiosis defective
External Movies 
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Cenix:36-c2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:36-c2 (PCR_reagent)
Remark  early embryonic: Passage Through Meiosis
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C47E12.5 Browse using GBrowse
Gene Graph