Ace View of Cenix:36-c2 | |||
Gene Inhibited | C47E12.5 (uba-1) | ||
Description of "C47E12.5" | uba-1 encodes a ubiquitin-activating enzyme orthologous to Saccharomyces cerevisiae UBA1 and human UBE1; UBA-1 is essential for embryogenesis and is required for germline development; by homology, UBA-1 is predicted to function in an ATP-dependent reaction that activates ubiquitin prior to its conjugation to proteins that will subsequently be degraded by the 26S proteasome; a uba-1 transcriptional reporter fusion is expressed in the larval intestine. | ||
Evidence for Inhibition | |||
External "C47E12.5" Links | ![]() ![]() ![]() |
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Embryonic | Emb Penetrance None reported | ||
Phenotype | Passage Through Meiosis defective |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:36-c2 (PCR_reagent) | ||
Remark | early embryonic: Passage Through Meiosis | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C47E12.5 | |||
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