Ace View of Cenix:38-f4 | |||
Gene Inhibited | Y116A8C.42 (snr-1) | ||
Description of "Y116A8C.42" | snr-1 encodes an ortholog of human small nuclear ribonucleoprotein Sm D3, a protein that forms part of a heptameric complex required for the biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm B ortholog (snr-2) snr-1 affects embryonic viability and the nuclear association and localization of P granules in embryos based on an RNAi assay, and also affects embryonic viability, growth, and fertility based on large-scale RNAi assays; snr-1 is expressed in embryos and is expressed in larvae and adults in muscles of the alimentary system, in body-wall muscle, in seam cells and other unidentified cells in larvae and in adults. | ||
KOG Annotation  | Small nuclear ribonucleoprotein Sm D3 |
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Evidence for Inhibition | |||
External "Y116A8C.42" Links | ![]() ![]() ![]() |
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Embryonic | Emb Penetrance None reported | ||
Phenotype | Osmotic Integrity defective |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:38-f4 (PCR_reagent) | ||
Remark | early embryonic: Osmotic Integrity | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of Y116A8C.42 | |||
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