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RNAi Experiment: Cenix:38-f4 Ace View of Cenix:38-f4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y116A8C.42 (snr-1)
Description of "Y116A8C.42"  snr-1 encodes an ortholog of human small nuclear ribonucleoprotein Sm D3, a protein that forms part of a heptameric complex required for the biogenesis and function of the snRNPs that catalyze mRNA splicing; in combination with the gene that encodes the human Sm B ortholog (snr-2) snr-1 affects embryonic viability and the nuclear association and localization of P granules in embryos based on an RNAi assay, and also affects embryonic viability, growth, and fertility based on large-scale RNAi assays; snr-1 is expressed in embryos and is expressed in larvae and adults in muscles of the alimentary system, in body-wall muscle, in seam cells and other unidentified cells in larvae and in adults.
KOG Annotation  Small nuclear ribonucleoprotein Sm D3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:17087979..17088535)
Transcript overlap: 425 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 362
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y116A8C.42" Links  Wormbase NCBI Phenobank 1
Cenix:38-f4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Osmotic Integrity defective
External Movies 
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hosting these data.)
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Cenix:38-f4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:38-f4 (PCR_reagent)
Remark  early embryonic: Osmotic Integrity
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y116A8C.42 Browse using GBrowse
Gene Graph