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RNAi Experiment: Cenix:41-e2 Ace View of Cenix:41-e2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F46F3.1 (ceh-27)
Description of "F46F3.1"  ceh-27 encodes a homeodomain protein of the NK-2 class that contains Drosophila scarecrow and human NKX-2 (OMIM:606727); CEH-27 activity is essential for embryogenesis and appears to be required for maintaining hypodermal integrity during movement as embryos lacking CEH-27 burst at a breach in the ventral hypodermis upon commencement of muscle contractions; CEH-27 expression is first detected in the ~100-cell embryo in what appear to be MS-derived cells while in later embryos expression is seen in a number of cells in the anterior head region.
KOG Annotation  Transcription factor tinman/NKX2-3, contains HOX domain
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:11664627..11665318)
Transcript overlap: 452 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 410
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F46F3.1" Links  Wormbase NCBI Phenobank 1
Cenix:41-e2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:41-e2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:41-e2 (PCR_reagent)
Remark  early embryonic: No significant defects seen.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F46F3.1 Browse using GBrowse
Gene Graph