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RNAi Experiment: Cenix:66-a8 Ace View of Cenix:66-a8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K10C2.4
Description of "K10C2.4"  K10C2.4 is orthologous to the human gene FUMARYLACETOACETATE (FAH; OMIM:276700), which when mutated leads to disease.
KOG Annotation  Fumarylacetoacetase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:6446788..6447682)
Transcript overlap: 666 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 603
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K10C2.4" Links  Wormbase NCBI Phenobank 1
Cenix:66-a8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:66-a8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:66-a8 (PCR_reagent)
Remark  Nearly 100% embryonic lethality. Escapers arrest at larval stage.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of K10C2.4 Browse using GBrowse
Gene Graph