Ace View of Cenix:71-e2 | |||
Gene Inhibited | C09H6.2 (lin-10) | ||
Description of "C09H6.2" | The lin-10 gene encodes a PDZ and PTB domain-containing protein that is homologous to mammalian Munc interacting proteins (Mint1, OMIM:602414) and is required for polarized protein localization; LIN-10 is required for proper localization of the LET-23 EGF receptor to the basolateral membrane of the vulval precursor cells and for proper postsynaptic localization of GLR-1, an AMPA-type glutamate receptor in interneurons; LIN-10 is detected in the cytoplasm, membrane, and at particularly high levels in the Golgi. | ||
KOG Annotation  | Beta amyloid precursor-binding protein PDZ domain |
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Evidence for Inhibition | |||
External "C09H6.2" Links | 1 2 | ||
Phenotype | WT |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:71-e2 (PCR_reagent) | ||
Remark | 3/3 tests are wt | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of C09H6.2 | |||