| RNAi Experiment: Cenix:71-f6 |
Ace View of Cenix:71-f6
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| Genes Inhibited |
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| Gene Inhibited |
F01G12.5 (let-2) |
| Description of "F01G12.5" |
let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization. |
| KOG Annotation |
Collagens (type IV and type XIII), and related proteins
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (X:16381108..16381701)
Transcript overlap: 512 nt |
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| Sliding Window |
Raw score: 470
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "F01G12.5" Links |
   1 2 |
| Cenix:71-f6 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
WT_postembryonic_morphology
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:71-f6 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:71-f6 (PCR_reagent) |
| Remark |
early embryonic: No significant defects. |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of F01G12.5 |
Browse using GBrowse
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