Link to F01G12.5b.1Link to F01G12.5b.2Link to F01G12.5aRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to C09G5.5Link to F26F12.1Link to F11G11.11Link to C34F6.3Link to ZK1010.7Link to T21B4.2Link to ZC513.8Link to C09G5.4Link to F14H12.1Link to C34F6.2Link to Y54E10BL.2geneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: Cenix:71-f6 Ace View of Cenix:71-f6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F01G12.5 (let-2)
Description of "F01G12.5"  let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization.
KOG Annotation  Collagens (type IV and type XIII), and related proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:16381108..16381701)
Transcript overlap: 512 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 470
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F01G12.5" Links  Wormbase NCBI Phenobank 1 2
Cenix:71-f6 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
(Please note that RNAiDB is not
hosting these data.)
/static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif
Help
Cenix:71-f6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:71-f6 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of F01G12.5 Browse using GBrowse
Gene Graph