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RNAi Experiment: Cenix:74-a3 Ace View of Cenix:74-a3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C43E11.10 (cdc-6)
Description of "C43E11.10"  cdc-6 encodes a homolog of an origin complex component (CDC6) which in yeast controls the start of DNA replication, and also has a distant paralog (Y39A1A.12) within the C. elegans genome; CDC-6 is superficially dispensable for embryonic viability, perhaps because of redundancy with Y39A1A.12.
KOG Annotation  Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:4268897..4269631)
Transcript overlap: 563 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 542
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C43E11.10" Links  Wormbase NCBI Phenobank 1
Cenix:74-a3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Sister Chromatid Separation abnormal (Cross-eyed)
External Movies 
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Cenix:74-a3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:74-a3 (PCR_reagent)
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C43E11.10 Browse using GBrowse
Gene Graph