Ace View of Cenix:76-d7 | |||
Gene Inhibited | Y111B2A.18 (rsp-3) | ||
Description of "Y111B2A.18" | rsp-3 encodes a putative ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro and the mRNA of rsp-3 is predominantly expressed in the germline. | ||
KOG Annotation  | Alternative splicing factor ASF/SF2 (RRM superfamily) |
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Evidence for Inhibition | |||
External "Y111B2A.18" Links | 1 | ||
Embryonic | Emb Penetrance None reported | ||
Phenotype | WT_postembryonic_morphology |
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External Movies (Please note that RNAiDB is not hosting these data.) |
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Laboratory | TH | ||
RNAi Reagent & Type | Cenix:76-d7 (PCR_reagent) | ||
Remark | early embryonic: Clear-cut result. | ||
Reference | Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." | ||
Delivery Method | Injection | ||
Date | 2005-3-24 | ||
Gene Plot of Y111B2A.18 | |||