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RNAi Experiment: Cenix:76-d7 Ace View of Cenix:76-d7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y111B2A.18 (rsp-3)
Description of "Y111B2A.18"  rsp-3 encodes a putative ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro and the mRNA of rsp-3 is predominantly expressed in the germline.
KOG Annotation  Alternative splicing factor ASF/SF2 (RRM superfamily)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:12686970..12687664)
Transcript overlap: 582 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 519
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y111B2A.18" Links  Wormbase NCBI Phenobank 1
Cenix:76-d7 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:76-d7 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:76-d7 (PCR_reagent)
Remark  early embryonic: Clear-cut result.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y111B2A.18 Browse using GBrowse
Gene Graph