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RNAi Experiment: Cenix:76-f6 Ace View of Cenix:76-f6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y110A7A.1 (hcp-6)
Description of "Y110A7A.1"  hcp-6 encodes a HEAT motif-containing protein that displays similarity to the XCAP-D2/CNAP1/Cnd1/YCS4 family of proteins that are homologous to the condensin complex subunit 1; HCP-6 activity is required during mitosis for some aspects of mitotic chromosome condensation, attachment of microtubules to kinetochores, mitotic chromosome alignment, and mitotic sister chromatid segregation; during interphase, HCP-6 is detectable in a punctate pattern in the nucleoplasm; at prophase, HCP-6 becomes associated with condensed chromosomes, colocalizing with the centromeric component HCP-3; HCP-6 localization to chromosomes depends upon the activity of HCP-3 and HCP-4, a C. elegans CENP-C-like protein.
KOG Annotation  Uncharacterized conserved protein related to condensin complex subunit 1
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:5167760..5168327)
Transcript overlap: 526 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 484
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y110A7A.1" Links  Wormbase NCBI Phenobank 1 2
Cenix:76-f6 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Sister Chromatid Separation abnormal (Cross-eyed)
External Movies 
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Cenix:76-f6 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:76-f6 (PCR_reagent)
Remark  early embryonic: Sister Chromatid Separation (Cross-eyed)
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of Y110A7A.1 Browse using GBrowse
Gene Graph