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RNAi Experiment: Cenix:82-c3 Ace View of Cenix:82-c3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C17E4.5 (pab-3)
Description of "C17E4.5"  pab-3 is orthologous to human PABPN1 (OMIM:602279, mutated in oculopharyngeal muscular dystrophy).
KOG Annotation  Splicing factor RNPS1, SR protein superfamily
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (I:9420600..9421989)
Transcript overlap: 1050 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 987
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.891
Wormbase (BLAST) RNAi primary
External "C17E4.5" Links  Wormbase NCBI Phenobank 1
Gene Inhibited  C17E4.11
Description of "C17E4.11"  Associated GO Term : S-adenosylmethionine-dependent methyltransferase activity
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (I:9420600..9421989)
Transcript overlap: 161 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 121
Relative score: 0.123 (Best raw score= for Gene )
Specificity index: 0.109
Wormbase (BLAST) RNAi primary
External "C17E4.11" Links  Wormbase NCBI Phenobank 1
Cenix:82-c3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:82-c3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:82-c3 (PCR_reagent)
Remark  Up to 50% embryonic lethality. All escapers die at early larval stage.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of C17E4.5 Browse using GBrowse
Gene Graph
Gene Plot of C17E4.11 Browse using GBrowse
Gene Graph