| RNAi Experiment: Cenix:89-f2 |
Ace View of Cenix:89-f2
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| Genes Inhibited |
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| Gene Inhibited |
T23D8.9 (sys-1) |
| Description of "T23D8.9" |
sys-1 encodes a novel protein that contains three divergent armadillo repeats; during gonadogenesis, SYS-1 functions in a Wnt/MAPK signaling pathway as a dosage-dependent beta-catenin-like transcriptional coactivator required for specification of distal cell fates; consistent with its role as a beta-catenin, SYS-1 interacts, in yeast two-hybrid and coimmunoprecipitation assays, with the POP-1/TCF transcription factor with which it can stimulate transcription via TCF binding sites; in two hybrid-assays, the POP-1/SYS-1 interaction requires the N-terminal beta-catenin binding domain of POP-1, and most of the SYS-1 protein; the SYS-1 expression pattern is not yet known. |
| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (I:9981568..9983132)
Transcript overlap: 1198 nt |
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| Sliding Window |
Raw score: 1051
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "T23D8.9" Links |
   1 2 |
| Cenix:89-f2 Phenotypes |
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| Embryonic |
Emb Penetrance None reported |
| Phenotype |
WT_postembryonic_morphology
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External Movies
(Please note that RNAiDB is not
hosting these data.) |
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| Cenix:89-f2 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
Cenix:89-f2 (PCR_reagent) |
| Remark |
early embryonic: No significant defects. |
| Reference |
Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...." |
| Delivery Method |
Injection |
| Date |
2005-3-24 |
| Gene Plot of T23D8.9 |
Browse using GBrowse
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