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RNAi Experiment: Cenix:98-h9 Ace View of Cenix:98-h9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  VF36H2L.1 (aph-1)
Description of "VF36H2L.1"  aph-1 encodes an unfamiliar protein predicted to have seven transmembrane domains; APH-1 is a component of the GLP-1/LIN-12 (Notch) pathway, is required maternally for embryonic viability, and also affects morphogenesis, egg laying, germ line proliferation, and translocation of APH-2 to the cell surface; with PEN-2, APH-1 is required for Notch pathway signaling, gamma-secretase cleavage of beta-amyloid precursor protein, and presenilin protein accumulation.
KOG Annotation  Predicted membrane protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9232450..9233704)
Transcript overlap: 710 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 626
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "VF36H2L.1" Links  Wormbase NCBI Phenobank 1
Cenix:98-h9 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  WT_postembryonic_morphology
External Movies 
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Cenix:98-h9 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  Cenix:98-h9 (PCR_reagent)
Remark  early embryonic: No significant defects.
Reference  Sonnichsen B et al. (2005) Nature "Full-genome RNAi profiling of early embryogenesis in Caenorhabditis ...."
Delivery Method  Injection
Date  2005-3-24
Gene Plot of VF36H2L.1 Browse using GBrowse
Gene Graph