RNAi Card Page

RNAi Experiment: JA:B0222.7

Ace View of JA:B0222.7

Genes Inhibited

Gene Inhibited

B0222.7 (col-145)

Description of "B0222.7"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

ePCR	Status: Unique_ePCR (V:9164285..9165879) Transcript overlap: 901 nt
Sliding Window	Raw score: 838 Relative score: 1 (This gene has the best score for this RNAi reagent) Specificity index: 0.225
Wormbase (BLAST)	RNAi primary

External "B0222.7" Links

Gene Inhibited

H06A10.2 (col-185)

Description of "H06A10.2"

Associated GO Term : structural constituent of cuticle

Evidence for Inhibition

Sliding Window

Raw score: 204
Relative score: 0.243 (Best raw score= for Gene )
Specificity index: 0.055

External "H06A10.2" Links

Gene Inhibited

B0222.8 (col-10)

Description of "B0222.8"

col-10 encodes a collagen protein; expressed exclusively in hypodermal cells

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window	Raw score: 374 Relative score: 0.446 (Best raw score= for Gene ) Specificity index: 0.101
Wormbase (BLAST)	RNAi primary

External "B0222.8" Links

Gene Inhibited

T13B5.4 (col-40)

Description of "T13B5.4"

col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 123
Relative score: 0.147 (Best raw score= for Gene )
Specificity index: 0.033

External "T13B5.4" Links

Gene Inhibited

EGAP7.1 (dpy-3)

Description of "EGAP7.1"

dpy-3 encodes a cuticular collagen; along with dpy-2, dpy-7, dpy-8, and dpy-10, dpy-3 is required postembryonically for annular furrow formation and/or maintenance; specifically, DPY-3 activity is required for proper assembly of the DPY-7 collagen into the mature extracellular matrix; during each cuticle synthetic period, dpy-3 mRNA is expressed approximately four hours prior to the secretion of new cuticle.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 315
Relative score: 0.376 (Best raw score= for Gene )
Specificity index: 0.085

External "EGAP7.1" Links

Gene Inhibited

F23H12.4 (sqt-3)

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 87
Relative score: 0.104 (Best raw score= for Gene )
Specificity index: 0.023

External "F23H12.4" Links

Gene Inhibited

F54D1.2 (col-126)

Description of "F54D1.2"

Associated GO Term : structural constituent of cuticle

Evidence for Inhibition

Sliding Window	Raw score: 73 Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "F54D1.2" Links

Gene Inhibited

F54B11.2 (col-44)

Description of "F54B11.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 280
Relative score: 0.334 (Best raw score= for Gene )
Specificity index: 0.075

External "F54B11.2" Links

Gene Inhibited

B0222.6 (col-144)

Description of "B0222.6"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window	Raw score: 400 Relative score: 0.477 (Best raw score= for Gene ) Specificity index: 0.108
Wormbase (BLAST)	RNAi primary

External "B0222.6" Links

Gene Inhibited

F54D1.3 (col-127)

Description of "F54D1.3"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window	Raw score: 73 Relative score: 0.087 (Best raw score= for Gene ) Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "F54D1.3" Links

Gene Inhibited

K04H4.1 (emb-9)

Description of "K04H4.1"

emb-9 encodes the alpha-1 chain of Type IV basement membrane collagen most closely equivalent to human COL4A1 (OMIM:120130) on the basis of biological function; EMB-9 forms heterotrimeric Type IV collagen with LET-2, the alpha-2-like chain, and is required for the assembly and/or secretion of LET-2; EMB-9 is essential for embryonic morphogenesis, particularly epidermal elongation, and for larval development; EMB-9 is expresed primarily by body wall muscles and some somatic cells of the gonad and is detected in nearly all basement membranes.

Evidence for Inhibition

Sliding Window

Raw score: 468
Relative score: 0.558 (Best raw score= for Gene )
Specificity index: 0.126

External "K04H4.1" Links

Gene Inhibited

C09G5.5 (col-80)

Description of "C09G5.5"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window