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RNAi Experiment: JA:C04F12.3 Ace View of JA:C04F12.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C04F12.3 (ikb-1)
Description of "C04F12.3"  ikb-1 encodes an ortholog of human BCL3 (OMIM:109560) that physically interacts with the checkpoint protein MRT-2; ikb-1(nr2019) and ikb-1(nr2027) mutants display no obvious phenotype other than shortened lifespan; mutation of BCL3 is frequently associated with recurring translocations found in the neoplastic cells of patients with chronic lymphocytic leukemia, and has been implicated in cell cycle control (perhaps via apoptosis).
KOG Annotation  Ankyrin repeat
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9686267..9688439)
Transcript overlap: 1474 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1310
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C04F12.3" Links  Wormbase NCBI
JA:C04F12.3 Phenotypes Help with Phenotypes
Phenotype  WT
JA:C04F12.3 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_C04F12.3 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of C04F12.3 Browse using GBrowse
Gene Graph