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RNAi Experiment: JA:C14A4.5 Ace View of JA:C14A4.5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C14A4.5 (crn-5)
Description of "C14A4.5"  Associated GO Term : 3'-5' exoribonuclease activity
KOG Annotation  Exosomal 3'-5' exoribonuclease complex, subunit Rrp46
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:10592518..10593440)
Transcript overlap: 678 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 615
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C14A4.5" Links  Wormbase NCBI
Gene Inhibited  C14A4.4 (crn-3)
Description of "C14A4.4"  crn-3 encodes a cell death-related nuclease, homologous to the 100 kDa polymyositis/scleroderma autoantigen (PM/Scl-100), that is required for normal levels of DNA degradation during apoptosis; PM/Scl-100 is a ribonuclease component of the multiexonuclease exosome complex, which processes or degrades several types of RNAs in yeast; crn-3(RNAi) animals show retarded growth and a low penetrance of embryonic lethality; CRN-3 promotes both DNA degradation and cell corpse engulfment, in a partially redundant pathway that includes CRN-2 but is parallel to CPS-6; CRN-3 is predicted to be mitochondrial.
Evidence for Inhibition 
ePCR Transcript overlap: 41 nt Explain types of evidence for RNAi inhibition
External "C14A4.4" Links  Wormbase NCBI
JA:C14A4.5 Phenotypes Help with Phenotypes
Larval  Gro
Phenotype  Pch
JA:C14A4.5 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_C14A4.5 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of C14A4.4 Browse using GBrowse
Gene Graph
Gene Plot of C14A4.5 Browse using GBrowse
Gene Graph