RNAi Experiment: JA:C25A11.3 |
Ace View of JA:C25A11.3
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Genes Inhibited |
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Gene Inhibited |
C25A11.4 (ajm-1) |
Description of "C25A11.4" |
ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (X:9111974..9113131)
Transcript overlap: 723 nt |
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Sliding Window |
Raw score: 597
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C25A11.4" Links |
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JA:C25A11.3 Phenotypes |
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Phenotype |
WT
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JA:C25A11.3 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_C25A11.3 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of C25A11.4 |
Browse using GBrowse
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