RNAi Experiment: JA:C37G2.6 |
Ace View of JA:C37G2.6
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Genes Inhibited |
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Gene Inhibited |
Y66A7A.6 (gly-8) |
Description of "Y66A7A.6" |
gly-8 encodes a predicted transmembrane polypeptide N-acetylgalactosaminyl transferase (ppGaNTase) similar to the essential Drosophila ppGaNTase encoded by Pgant35A; by homology, GLY-8 is predicted to function as a Golgi enzyme that catalyzes transfer of N-acetylgalactosamine to serine and threonine-containing acceptor peptides, thus initiating mucin-type O-glycosylation; as loss of gly-8 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GLY-8 in C. elegans development and/or behavior is not yet known. |
KOG Annotation  |
Polypeptide N-acetylgalactosaminyltransferase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:11626353..11627991)
Transcript overlap: 809 nt |
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Sliding Window |
Raw score: 683
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y66A7A.6" Links |
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JA:C37G2.6 Phenotypes |
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Phenotype |
WT
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JA:C37G2.6 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_C37G2.6 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y66A7A.6 |
Browse using GBrowse
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