Ace View of JA:C47E12.5 | |||
Gene Inhibited | C47E12.5 (uba-1) | ||
Description of "C47E12.5" | uba-1 encodes a ubiquitin-activating enzyme orthologous to Saccharomyces cerevisiae UBA1 and human UBE1; UBA-1 is essential for embryogenesis and is required for germline development; by homology, UBA-1 is predicted to function in an ATP-dependent reaction that activates ubiquitin prior to its conjugation to proteins that will subsequently be degraded by the 26S proteasome; a uba-1 transcriptional reporter fusion is expressed in the larval intestine. | ||
Evidence for Inhibition | |||
External "C47E12.5" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Adult | Sck Ste |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_C47E12.5 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of C47E12.5 | |||