RNAi Experiment: JA:E01A2.g |
Ace View of JA:E01A2.g
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Genes Inhibited |
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Gene Inhibited |
E01A2.3 (lin-44) |
Description of "E01A2.3" |
lin-44 encodes one of five C. elegans Wnt signaling ligands; during development, LIN-44 activity is required non-cell-autonomously for polarity specification of asymmetric cell divisions of the B, U, and F cells in the male, and the T cell in males and hermaphrodites; in addition, LIN-44 functions redundantly with MOM-2 and CWN-2 to pattern the P7.p lineage during vulval development; lin-44 expression begins at the 1.5-fold stage of embryogenesis in the posterior hypodermal cells hyp10 and hyp11; during later embryonic stages additional expression in hyp8 and hyp9 is detected; reporter fusions and in situ hybridization studies also reveal weak and inconsistent expression in the anchor cell of the somatic gonad. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:4127141..4129452)
Transcript overlap: 904 nt |
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Sliding Window |
Raw score: 820
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "E01A2.3" Links |
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JA:E01A2.g Phenotypes |
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Phenotype |
WT
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JA:E01A2.g Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_E01A2.g (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of E01A2.3 |
Browse using GBrowse
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