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RNAi Experiment: JA:E03G2.3 Ace View of JA:E03G2.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  E03G2.3 (mec-5)
Description of "E03G2.3"  mec-5 encodes a collagen unique in the number of Gly-X-Y repeats and in the composition of amino acids surrounding these repeats; MEC-5 is required for normal mechanosensory response to gentle touch and for the proper functioning of the touch receptor neurons; mec-5 interacts genetically with mec-4 and mec-10 which encode degenerins (ion channels) expressed in the touch neurons, mec-9, which encodes a protein containing EGF-like and Kunitz/protease inhibitor domains secreted by the touch neurons, and mec-12, which encodes an alpha-tubulin expressed in the touch neurons; these genetic interactions suggest that MEC-5 may play a role in anchoring the degenerin complex to the extracellular matrix; MEC-5 is produced and secreted by hypodermal cells.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:15945707..15947565)
Transcript overlap: 462 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 410
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.556
Wormbase (BLAST) RNAi primary
External "E03G2.3" Links  Wormbase NCBI
Gene Inhibited  K07E8.12 (sri-44)
Evidence for Inhibition 
Sliding Window Raw score: 327
Relative score: 0.798 (Best raw score= for Gene )
Specificity index: 0.444
External "K07E8.12" Links  Wormbase NCBI
JA:E03G2.3 Phenotypes Help with Phenotypes
Phenotype  WT
JA:E03G2.3 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_E03G2.3 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of E03G2.3 Browse using GBrowse
Gene Graph
Gene Plot of K07E8.12 Browse using GBrowse
Gene Graph