Ace View of JA:F07A5.7 | |||
Gene Inhibited | F07A5.7 (unc-15) | ||
Description of "F07A5.7" | The unc-15 gene encodes a paramyosin ortholog; UNC-15 protein physically interacts with MHC A, one isoform of myosin heavy chain (MHC) in striated muscle; UNC-15 accumulation is decreased in the absence of UNC-54 (myosin B), implying that degradation of UNC-15 is inhibited by its binding myosin B; conversely, myosin B (but not MYO-3/myosin A) fails to accumulate in unc-15 mutants. | ||
KOG Annotation  | Myosin class II heavy chain |
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Evidence for Inhibition | |||
External "F07A5.7" Links | |||
Adult | Egl Unc |
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Phenotype | Prl |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_F07A5.7 (PCR_reagent) | ||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | ||
Date | 2000-11-16 | ||
Gene Plot of F07A5.7 | |||