Link to F11A6.1aLink to F11A6.1bRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: JA:F11A6.1 Ace View of JA:F11A6.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F11A6.1 (kpc-1)
Description of "F11A6.1"  kpc-1 encodes two isoforms of a Kex2/subtilisin-like proprotein convertase that is a member of the subtilase family of calcium-dependent serine endoproteinases that includes mammalian furin (OMIM:136950) and Saccharomyces cerevisiae Kex2p; KPC-1 is required for normal growth and locomotion and is likely responsible for the processing of transforming growth factor (TGF) beta proproteins encoded by daf-7, dbl-1, and unc-129.
KOG Annotation  Subtilisin-like proprotein convertase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:11679113..11680769)
Transcript overlap: 1188 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1104
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F11A6.1" Links  Wormbase NCBI
JA:F11A6.1 Phenotypes Help with Phenotypes
Phenotype  WT
JA:F11A6.1 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F11A6.1 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of F11A6.1 Browse using GBrowse
Gene Graph