RNAi Experiment: JA:F11A6.1 |
Ace View of JA:F11A6.1
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Genes Inhibited |
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Gene Inhibited |
F11A6.1 (kpc-1) |
Description of "F11A6.1" |
kpc-1 encodes two isoforms of a Kex2/subtilisin-like proprotein convertase that is a member of the subtilase family of calcium-dependent serine endoproteinases that includes mammalian furin (OMIM:136950) and Saccharomyces cerevisiae Kex2p; KPC-1 is required for normal growth and locomotion and is likely responsible for the processing of transforming growth factor (TGF) beta proproteins encoded by daf-7, dbl-1, and unc-129. |
KOG Annotation  |
Subtilisin-like proprotein convertase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:11679113..11680769)
Transcript overlap: 1188 nt |
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Sliding Window |
Raw score: 1104
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F11A6.1" Links |
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JA:F11A6.1 Phenotypes |
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Phenotype |
WT
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JA:F11A6.1 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_F11A6.1 (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of F11A6.1 |
Browse using GBrowse
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