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RNAi Experiment: JA:F12F6.6 Ace View of JA:F12F6.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F12F6.6 (sec-24.1)
Description of "F12F6.6"  sec-24.1 encodes one of two C. elegans Sec24 homologs; in Saccharomyces cerevisiae, Sec24 is a member of the Sec24-Sec23 subunit of the COPII coat complex, assembly of which is essential for the first step of secretory protein transport from the endoplasmic reticulum (ER) to the Golgi; by homology with Sec24, SEC-24.1 is predicted to facilitate vesicle cargo selection, and likely contains multiple, independent sites for binding to secreted proteins; loss of sec-24.1 activity via RNAi indicates that SEC-24.1 is required for cuticle secretion and oogenesis.
KOG Annotation  Vesicle coat complex COPII, subunit SFB3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:11562315..11563492)
Transcript overlap: 1132 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1090
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F12F6.6" Links  Wormbase NCBI
JA:F12F6.6 Phenotypes Help with Phenotypes
Adult  Sck
Ste
JA:F12F6.6 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F12F6.6 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of F12F6.6 Browse using GBrowse
Gene Graph