Ace View of JA:F12F6.6 | |||
Gene Inhibited | F12F6.6 (sec-24.1) | ||
Description of "F12F6.6" | sec-24.1 encodes one of two C. elegans Sec24 homologs; in Saccharomyces cerevisiae, Sec24 is a member of the Sec24-Sec23 subunit of the COPII coat complex, assembly of which is essential for the first step of secretory protein transport from the endoplasmic reticulum (ER) to the Golgi; by homology with Sec24, SEC-24.1 is predicted to facilitate vesicle cargo selection, and likely contains multiple, independent sites for binding to secreted proteins; loss of sec-24.1 activity via RNAi indicates that SEC-24.1 is required for cuticle secretion and oogenesis. | ||
KOG Annotation  | Vesicle coat complex COPII, subunit SFB3 |
||
Evidence for Inhibition | |||
External "F12F6.6" Links | |||
Adult | Sck Ste |
||
Laboratory | JA | ||
RNAi Reagent & Type | sjj_F12F6.6 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of F12F6.6 | |||