Ace View of JA:F18A1.5 | |||
Gene Inhibited | F18A1.5 | ||
Description of "F18A1.5" | F18A1.5 encodes the C. elegans ortholog of the replication protein A (RPA) large subunit; by homology, the F18A1.5 gene product is predicted to function as a DNA binding and oligonucleotide oligosaccharide binding (OB) protein that is required for DNA replication, repair, and recombination; large-scale RNAi screens indicate that the product of F18A1.5 is essential for embryonic development, and that in yeast two-hybrid assays interacts with the product of M04F3.1, the RPA medium subunit; in situ hybridization studies indicate that F18A1.5 transcripts are expressed in germ cells. | ||
KOG Annotation  | Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins |
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Evidence for Inhibition | |||
External "F18A1.5" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Laboratory | JA | ||
RNAi Reagent & Type | sjj_F18A1.5 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of F18A1.5 | |||