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RNAi Experiment: JA:F18G5.2 Ace View of JA:F18G5.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F18G5.2 (pes-8)
Description of "F18G5.2"  pes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:9253460..9255158)
Transcript overlap: 800 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 674
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F18G5.2" Links  Wormbase NCBI
JA:F18G5.2 Phenotypes Help with Phenotypes
Adult  Egl
Ste
Phenotype  Adl
Prz
JA:F18G5.2 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F18G5.2 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of F18G5.2 Browse using GBrowse
Gene Graph