Ace View of JA:F18G5.2 | |||
Gene Inhibited | F18G5.2 (pes-8) | ||
Description of "F18G5.2" | pes-8 encodes a novel protein that contains a proline-rich region and a predicted transmembrane domain, but no otherwise recognizably conserved domains; pes-8 was identified in promoter trapping screens and based on large-scale RNA-mediated interference (RNAi) screens, appears to be required for egg laying, germline development, locomotion, and regulation of adult lifespan; a pes-8 reporter is expressed at the cell surfaces of the spermathecal valve cell, the uterine wall, the vulva, and the rectal epithelium; strong expression is also detected in the uterus during its development; PES-8 may be required for normal morphology of the openings of the spermathecal valve, the vulva, and the rectum, a hypothesis consistent with its expression pattern and RNAi phenotype. | ||
Evidence for Inhibition | |||
External "F18G5.2" Links | |||
Adult | Egl Ste |
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Phenotype | Adl Prz |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_F18G5.2 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of F18G5.2 | |||