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RNAi Experiment: JA:F42G8.11 Ace View of JA:F42G8.11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F42G8.11 (sph-1)
Description of "F42G8.11"  sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
Evidence for Inhibition 
ePCR Status: Best_ePCR (IV:8132300..8133867)
Transcript overlap: 788 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 683
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.899
Wormbase (BLAST) RNAi primary
External "F42G8.11" Links  Wormbase NCBI
Gene Inhibited  F42G8.12 (isp-1)
Description of "F42G8.12"  isp-1 encodes a Rieske iron sulphur protein (ISP) which is a subunit of the mitochondrial complex III in the mitochondrial membrane; the subunits are highly conserved in all mitochondria and aerobic bacteria; mitochondrial complex III catalyses electron transport from ubiquinol to cytochrome c; isp-1 mutants show low oxygen consumption, a decreased sensitivity to reactive oxygen species and increased lifespan suggesting that mitochondrial electron transport is a key factor affecting life span; isp-1 affects the rates of physiological processes like reproduction and development and also affects behavior.
KOG Annotation  Ubiquinol cytochrome c reductase, subunit RIP1
What's a KOG?
Evidence for Inhibition 
ePCR Status: Bottom50_percentile_ePCR (IV:8132300..8133867)
Transcript overlap: 98 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 77
Relative score: 0.113 (Best raw score= for Gene )
Specificity index: 0.101
External "F42G8.12" Links  Wormbase NCBI
JA:F42G8.11 Phenotypes Help with Phenotypes
Phenotype  WT
JA:F42G8.11 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F42G8.11 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of F42G8.12 Browse using GBrowse
Gene Graph
Gene Plot of F42G8.11 Browse using GBrowse
Gene Graph