Ace View of JA:F52B10.1 | |||
Gene Inhibited | F52B10.1 (nmy-1) | ||
Description of "F52B10.1" | nmy-1 encodes a class II non-muscle myosin heavy chain related to Drosophila zipper, which plays a role in several aspects of embryonic morphogenesis; in C. elegans, NMY-1 is required for embryonic elongation and establishment of normal body morphology; mutations in nmy-1 suppress the hypercontraction phenotype produced by mutations in mel-11, a myosin phosphatase that regulates actomyosin filament contraction; in addition, NMY-1 may partner with MLC-4, myosin light chain 4, during elongation; NMY-1 expression is detected during embryogenesis, particularly at the onset of elongation. | ||
KOG Annotation  | Myosin class II heavy chain |
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Evidence for Inhibition | |||
External "F52B10.1" Links | |||
Embryonic | Emb Penetrance 40 % | ||
Adult | Bmd Dpy Stp brood size (1 out of 5) Unc |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_F52B10.1 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of F52B10.1 | |||