Ace View of JA:F54E7.4 | |||
Gene Inhibited | F54E7.3 (par-3) | ||
Description of "F54E7.3" | par-3 encodes a PDZ domain-containing protein orthologous to mammalian atypical PKC isotype-specific interacting protein (ASIP) and Drosophila Bazooka that is required maternally for polarization of the zygote along the anterior-posterior (A-P) axis; PAR-3, PAR-6, and PKC-3 form a complex that localizes to the anterior cytoplasmic cortex of the one- and two-cell embryo; this localization is regulated spatially by PAR-2, which segregates to the posterior cortex. | ||
Evidence for Inhibition | |||
External "F54E7.3" Links | |||
Embryonic | Emb Penetrance 80 % | ||
Adult | Bmd Muv Pvl |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_F54E7.4 (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of F54E7.3 | |||