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RNAi Experiment: JA:F56G4.3 Ace View of JA:F56G4.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F56G4.3
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:11357915..11358982)
Transcript overlap: 750 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 708
Specificity index: 0.5
Wormbase (BLAST) RNAi primary
External "F56G4.3" Links  Wormbase NCBI
Gene Inhibited  F56G4.2 (pes-2)
Description of "F56G4.2"  pes-2 encodes a protein containing a predicted signal sequence and an F-box, a motif believed to mediate protein-protein interactions either with homologs of yeast Skp1p or with other proteins; pes-2 was identified in two different molecular screens, a promoter-trapping screen and a screen for genes that are preferentially transcribed in pre-gastrulation embryos; by homology, pes-2 is predicted to function in ubiquitin-proteasome mediated protein degradation; pes-2 may also play a role in lifespan determination, as its expression is downregulated in young adult worms containing loss-of-function mutations in the daf-2 insulin/IGF-1 receptor, and loss of pes-2 function via RNA-mediated interference (RNAi) can enhance animal survival rates; pes-2 expression is first detected in 4- to 8-cell stage embryos, continues in early embryogenesis in cells from the AB, MS, and E founder cell lineages, and in later embryogenesis is becomes restricted to hypodermal cells; expression in larvae and adults has not yet been reported.
Evidence for Inhibition 
Sliding Window Raw score: 708
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.5
Wormbase (BLAST) RNAi primary
External "F56G4.2" Links  Wormbase NCBI
JA:F56G4.3 Phenotypes Help with Phenotypes
Phenotype  WT
JA:F56G4.3 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F56G4.3 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of F56G4.3 Browse using GBrowse
Gene Graph
Gene Plot of F56G4.2 Browse using GBrowse
Gene Graph